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JointRenew2 TM Doctors' Choice Medical Nutrients TM A Pharmaceutical Grade Dietary Supplement Shown Effective for Improving Cartilage Condition, Relieving Pain, and Increasing Mobility for People Who Suffer from Osteoarthritis and Rheumatoid Arthritis Contains: Glucosamine Sulfate, Collagen, Chondroitin Sulfate, Vitamin-C, Calcium, and Zinc $25.95/bottle - 120 Capsules (1 month supply) Go to Shoppoing Cart to see multi-pack discounts at $17.00 per bottle!

Glucosamine sulfate and chondroitin sulfate are two natural substances that are found in normal joint tissue. These two substances are the foundation for the natural arthritis program recommended by Jason Theodosakis, M.D., M.S., M.P.H. in his best selling book, The Arthritis Cure. According to Dr. Theodosakis, glucosamine and chondroitin sulfate, when added to your regular diet in supplemental form, have been shown to reverse damage in joint cartilage and have produced tremendous results in reducing the pain and discomfort caused by arthritis.

JointRenew contains 1,000 mg. of 100% pure cyrstalline Glucosamine Sulfate and 400 mg. of 100% pure Chondroitin Sulfate per daily dosage, the highest potency and quality pharmaceutical grade ingredients on the market. In addition, JointRenew also contains 700 mg. Collagen, which is a naturally occurring source for both glucosamine and chondroitin sulfates. Collagen (protein) is essential for the growth and development of all body tissue, and is especially important for healthy cartilage. Other essential ingredients include 300 mg. V-C (which is essential for proper assimilation of glucosamine and chondroitin), 100 mg. Calcium, and 20 mg. Zinc.

You should also know that JointRenew is the only combination product on the market with high potency collagen, which gives you increased amounts of "natural" glucosamine sulfate and chondroitin sulfate. You will get better results from taking JointRenew with collagen than you will by taking a simple combination product that only contains glucosamine and chondroitin sulfates. Not only does this combination makes JointRenew the most effective product available today, you will find our prices to be among the lowest on the market.

When taking JointRenew, some people notice an effect within a few days, while others may have to wait up to eight weeks. In rare cases, three to four months are needed to notice an effect. Directions for use: take 4 capsules per day; two capsules with meals 2 times daily. It is recommended that you take this and most other nutritional supplementation at least 30 minutes before or after any prescriptions.

Using JointRenew with anti-inflammatory pills (NSAIDS) is safe and can in fact be helpful. Evidence suggests that using glucosamine counteracts the normal decrease in proteoglycan (cartilage) synthesis associated with the use of some NSAIDS. Fortunately, most patients are able to stop using their NSAIDs after taking glucosamine and chondroitin for two to eight weeks. Some who have been taking NSAIDs for decades have been able to get off them completely. Other factors that can positively contribute to your joint health are proper nutrition and a healthy diet, slimming down to your ideal body weight, avoiding depression and actively treating it should it exist.

Who is a Good Candidate to Take Joint Renew?

The conditions that show the greatest response are rheumatoid arthritis and osteoarthritis. If you have grown weary of traditional prescriptions, and their negative side effects that only cover up symptoms and neglect to treat the root cause, then you are an excellent candidate to begin a program of JointRenew. The human body is an amazing organism that constantly strives to attain a state of balance or equilibrium. In the appropriate environment, with the proper building blocks, the human body can rebuild lost cartilage.

Remember, it took many years for your body to get to the state of pain that it is currently in. This product is not a "quick-fix" anti-inflammatory or pain killer that neglects or ignores the underlying cause, it is an all natural, nontoxic nutriceutical that helps your body heal itself. What you will notice first is a decrease in pain, and an increase in mobility.

Why Cartilage Fails

Cartilage has two key structural components: very strong collagen fibers which are made of protein, and a reinforced gel, which is made of proteoglycans (actually chondroitin sulfate molecules) which weave through the collagen fibers in every direction, and water, which fills up the space in between. The collagen and the proteoglycans are manufactured by cells called chondrocytes (which also contain chondroitin sulfate) scattered about the cartilage matrix, they also dispose of worn out collagen and proteoglycans. Free-floating chondroitin sulfate, with its sulfur atoms, grab nutrients for the chondrocytes. Since cartilage does not have a network of blood vessels to bring in oxygen and nutrients and carry away waste products, it depends on the steady ebb and flow of fluid for nourishment and cleansing.

Repeated stress to a joint can weaken or damage cartilage, leading to discomfort and reduced mobility. Cartilage repairs itself very slowly, due to poor nutrient supply and the fact that joints are seldom given the time to rest. The abnormal buildup of free radicals from many causes, including diet, inflammation and infection, triggers release of excess enzymes that break cartilage down, and inhibits production of proteoglycans and chondroitin sulfate.

What does Glucosamine do?

Glucosamine sulfate, made up of sugar and an amino acid, makes up 50% of hyaluronic acid, which is the “base” of the proteoglycans, and also is a key factor in stimulating the chondrocytes to produce new collagen, proteoglycans and chondroitin sulfate to replace the old. It is the starting point for the synthesis of many important macro-molecules that make up many of the body's tissues. A deficiency of glucosamine can reduce the rate of production of these important macromolecules thereby leading to specific tissue weakness. In certain cases of trauma to the tissues, the amount of glucosamine normally synthesized by the body is insufficient. The tissues containing these glucosamine macromolecules include tendons and ligaments, cartilage, synovial fluid, mucus membranes, several structures in the eye, blood vessels, and heart valves. Glucosamine helps to reduce pain and improve joint function in those afflicted with osteoarthritis. It has also been shown to inhibit at least two of the enzymes that degrade cartilage and has certain anti-reactive properties. This means that glucosamine actually blunts the damaging effects of certain chemicals on the cartilage in joints.

Supplements of glucosamine sulfate may help to restore normal chondrocyte metabolism, which in turn may facilitate reversing cartilage breakdown and reducing pain. Glucosamine sulfate can increase the chance for positive results in a short period of time for a variety of problems including: breakdown and inflammation of the synovial fluids, damage to the tissues, ligaments and muscles, inflamed disc and sciatica nerve, inflamed joints associated with aging, loss of elasticity in the invertebral discs.

Glucosamine vs. Traditional Treatments

Improvements occur more slowly with glucosamine sulfate than with over-the-counter arthritis medications (NSAIDs), but eventually glucosamine overtakes the NSAIDs in terms of effectiveness. In one study that compared glucosamine sulfate to ibuprofen, pain scores decreased faster in the first two weeks in the ibuprofen group, however, by the fourth week of the study, the group receiving the glucosamine sulfate was doing significantly better than the ibuprofen group. In another study 30 patients with osteoarthritis were divided into two groups, half received glucosamine sulfate, while the control group received a traditional arthritic drug formula. Both groups showed improvement in the early stages of the study, with the glucosamine sulfate group improving to a significantly greater extent after the first several weeks. By the end of the study, the control group using the arthritis formula reverted almost to pretreatment levels. In addition, glucosamine sulfate is virtually free of side effects, there are no known contra-indications, it is readily absorbed from the intestines, stays in the blood for several hours and very little is excreted. In contrast, conventional arthritis medications can cause relatively severe side effects. Current medical treatment for osteoarthritis simply suppresses symptoms, and since it does not address the underlying causes, it actually promotes the disease process.

Glucosamine Testing Results

What are Chondroitin Sulfates?

Chondroitin sulfates are long molecular chains that have a negative electrical charge and are composed of sugar units that very effectively attract and capture fluid giving cartilage it’s sponge-like quality. Chondroitin sulfate is essential to cartilage growth and repair. Without enough chondroitin sulfate, cartilage integrity seriously declines. Chondroitin sulfate production declines with age, is disrupted by stress or injury, and is also inhibited by the very anti-inflammatory and corticosteroid drugs often prescribed for arthritis!

Chondroitin sulfate supplements help diminish the cartilage-destroying enzymes in joints affected by osteoarthritis. Chondroitin sulfate also accelerates wound and ulcer healing by helping chondrocytes form collagen fibers to close the opening, promotes cardiovascular health by activating a fat-digesting enzyme called lipoprotein lipase on the inner surface of the capillaries, which helps blood flow through the capillaries.

Chondroprotective Checklist

Glucosamine sulfate and chondroitin sulfate used together successfully address the causes of cartilage damage at the cellular level, between them they meet all of the requirements for "true" chondroprotective agents: enhancement of cartilage cell macro-molecular synthesis (GAGs, proteoglycans, collagens, proteins, RNA and DNA); enhancement of the synthesis of hyaluronic acid; inhibition of enzymes which degrade cartilage cell macro-molecules; dislodging of thrombi (clots), fibrin, lipids, and cholesterol deposits in synovial spaces in joints and in blood vessels surrounding them; reduce joint pain and synovitis (irritation of the synovial membrane).

The Importance of Collagen

Collagen, or hydrolyzed amino acids from protein, is essential for the growth and development of all body tissue, and is especially important for healthy cartilage. It is important to note that the combination of the proteoglycans (glucosamine sulfate and chondroitin sulfate) and proteins (collagen) not only protect the cartilage, but also provide the building blocks required to rebuild lost cartilage to restore the joint to a normal state. Protein is absolutely essential for healthy brain tissue and a healthy heart, to maintain our muscles, and even our hair, skin and nails. Because collagen is a key building block for several processes of the body, many people notice their nails grow faster, their hair strands get thicker, and their skin becomes softer.

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